Disruption of type I interferon signaling causes sexually dimorphic dysregulation of anti-viral cytokines

Disruption of type I interferon signaling causes sexually dimorphic dysregulation of anti-viral cytokines

Type I interferons (IFNs) play a crucial role in the establishment of an antiviral state via signaling through their cognate type I IFN receptor (IFNAR). In this study, a replication-competent but highly attenuated strain of VSV (rVSVΔm51) carrying a deletion at position 51 of the matrix protein to...

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Bibliographic Details
Main Authors: Maedeh Darzianiazizi, Katrina E. Allison, Raveendra R. Kulkarni, Shayan Sharif, Khalil Karimi, Byram W. Bridle
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cytokine: X
Subjects:
Type I interferon
Type I interferon receptor
Interferon signaling
Cytokine response
Sex as a biological variable
Online Access:http://www.sciencedirect.com/science/article/pii/S2590153221000033

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http://www.sciencedirect.com/science/article/pii/S2590153221000033

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