Peroxynitrite decomposition catalyst reduces vasopressin requirement in ovine MRSA sepsis

Peroxynitrite decomposition catalyst reduces vasopressin requirement in ovine MRSA sepsis

Abstract Background Sepsis is one of the most frequent causes of death in the intensive care unit. Host vascular hypo-responsiveness to vasopressors during septic shock is one of the challenging problems. This study tested the hypothesis that adjunct therapy with peroxynitrite decomposition catalyst...

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Bibliographic Details
Main Authors: Osamu Fujiwara, Satoshi Fukuda, Ernesto Lopez, Yaping Zeng, Yosuke Niimi, Douglas S. DeWitt, David N. Herndon, Donald S. Prough, Perenlei Enkhbaatar
Format: Article
Language:English
Published: SpringerOpen 2019-09-01
Series:Intensive Care Medicine Experimental
Subjects:
Peroxynitrite decomposition catalyst
WW-85
Arginine vasopressin
Septic shock
Vascular hypo-responsiveness
Refractory shock
Online Access:http://link.springer.com/article/10.1186/s40635-019-0227-4

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http://link.springer.com/article/10.1186/s40635-019-0227-4

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