Bone marrow transplantation restores follicular maturation and steroid hormones production in a mouse model for primary ovarian failure.

Recent studies suggest that bone marrow stem cells (BMSCs) are promising grafts to treat a variety of diseases, including reproductive dysfunction. Primary ovarian failure is characterized by amenorrhea and infertility in a normal karyotype female, with an elevated serum level of follicle-stimulatin...

Full description

Bibliographic Details
Main Authors: Mohsen Ghadami, Ebtehal El-Demerdash, Dong Zhang, Salama A Salama, Awadh A Binhazim, Anthony E Archibong, Xinlei Chen, Billy R Ballard, M Ram Sairam, Ayman Al-Hendy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3296713?pdf=render