Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors

The dynamic organization of signaling cascades inside primary cilia is key to signal propagation. Yet little is known about the dynamics of ciliary membrane proteins besides a possible role for motor-driven Intraflagellar Transport (IFT). To characterize these dynamics, we imaged single molecules of...

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Bibliographic Details
Main Authors: Fan Ye, David K Breslow, Elena F Koslover, Andrew J Spakowitz, W James Nelson, Maxence V Nachury
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-08-01
Series:eLife
Subjects:
IFT
Online Access:https://elifesciences.org/articles/00654