CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool

Bacteriophages are pervasive viruses that infect bacteria, relying on their genetic machinery to replicate. In order to protect themselves from this kind of invader, bacteria developed an ingenious adaptive defence system, clustered regularly interspaced short palindromic repeats (CRISPR). Researche...

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Bibliographic Details
Main Authors: Alexandre Loureiro, Gabriela Jorge da Silva
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/8/1/18