Promoter-proximal elongation regulates transcription in archaea

Transcription in archaea is known to be regulated through the recruitment of RNA polymerase to promoters. Here, the authors show that the archaeon Saccharolobus solfataricus regulates transcription globally through a rate-limiting promoter-proximal elongation step.

Bibliographic Details
Main Authors: Fabian Blombach, Thomas Fouqueau, Dorota Matelska, Katherine Smollett, Finn Werner
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25669-2