Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents

Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents

RNAi screens have implicated hundreds of host proteins as HIV-1 dependency factors (HDFs). While informative, these early studies overlap poorly due to false positives and false negatives. To ameliorate these issues, we combined information from the existing HDF screens together with new screens per...

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Bibliographic Details
Main Authors: Jian Zhu, Teresa Davoli, Jill M. Perriera, Christopher R. Chin, Gaurav D. Gaiha, Sinu P. John, Frederic D. Sigiollot, Geng Gao, Qikai Xu, Hongjing Qu, Thomas Pertel, Jennifer S. Sims, Jennifer A. Smith, Richard E. Baker, Louise Maranda, Aylwin Ng, Stephen J. Elledge, Abraham L. Brass
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714008146

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http://www.sciencedirect.com/science/article/pii/S2211124714008146

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