Physicochemical Properties and In Vitro Cytotoxicity Studies of Chitosan as a Potential Carrier for Dicer-Substrate siRNA

Recently, Dicer-substrate small interfering RNA (DsiRNA) has gained attention owing to its greater potency over small interfering RNA (siRNA). However, the use of DsiRNA is restricted by its rapid degradation in vitro. To address this issue, chitosan nanoparticulate deliver yplatform for the Dicer-s...

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Bibliographic Details
Main Authors: Maria Abdul Ghafoor Raja, Haliza Katas, Zariyantey Abd Hamid, Nur Atiqah Razali
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Nanomaterials
Online Access:http://dx.doi.org/10.1155/2013/653892