Saccharomyces cerevisiae mannan induces sheep beta-defensin-1 expression via Dectin-2-Syk-p38 pathways in ovine ruminal epithelial cells

Abstract The rumen epithelium of sheep serves as an immune interface with the environment and secretes antimicrobial peptides with bactericidal function against various pathogens. Sheep beta-defensin-1 (SBD-1), an antimicrobial peptide, is secreted from ovine ruminal epithelial cells (OREC) in respo...

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Bibliographic Details
Main Authors: Xin Jin, Man Zhang, Gui-fang Cao, Yin-feng Yang
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-019-0624-4