Ursolic and Oleanolic Acids Induce Mitophagy in A549 Human Lung Cancer Cells

Ursolic and Oleanolic Acids Induce Mitophagy in A549 Human Lung Cancer Cells

Ursolic and oleanolic acids are natural isomeric triterpenes known for their anticancer activity. Here, we investigated the effect of triterpenes on the viability of A549 human lung cancer cells and the role of autophagy in their activity. The induction of autophagy, the mitochondrial changes and si...

Full description

Bibliographic Details
Main Authors: Nayeli Shantal Castrejón-Jiménez, Kahiry Leyva-Paredes, Shantal Lizbeth Baltierra-Uribe, Juan Castillo-Cruz, Marcia Campillo-Navarro, Alma Delia Hernández-Pérez, Alexandra Berenice Luna-Angulo, Rommel Chacón-Salinas, Ramón Mauricio Coral-Vázquez, Iris Estrada-García, Luvia Enid Sánchez-Torres, Carlos Torres-Torres, Blanca Estela García-Pérez
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
ursolic acid
oleanolic acid
mitophagy
A549 human lung cancer cells
reactive oxygen species
PINK1/Parkin
Online Access:https://www.mdpi.com/1420-3049/24/19/3444

Internet

https://www.mdpi.com/1420-3049/24/19/3444

Similar Items