Anagrelide Modulates Proplatelet Formation Resulting in Decreased Number and Increased Size of Platelets

Abstract. We retrospectively evaluated 48 essential thrombocythemia (ET) patients who were treated in our institute (male/female, 14/34, median age, 61.5 years). In 14 patients treated with anagrelide (ANA), the degree of platelet count reduction (median, −56.6%) was strongly correlated with increas...

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Bibliographic Details
Main Authors: Naohiro Miyashita, Masahiro Onozawa, Shota Yokoyama, Daisuke Hidaka, Koji Hayasaka, Shinji Kunishima, Takanori Teshima
Format: Article
Language:English
Published: Wolters Kluwer 2019-08-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000268