Proximity assays for sensitive quantification of proteins
Proximity assays are immunohistochemical tools that utilise two or more DNA-tagged aptamers or antibodies binding in close proximity to the same protein or protein complex. Amplification by PCR or isothermal methods and hybridisation of a labelled probe to its DNA target generates a signal that enab...
Main Authors: | Christina Greenwood, David Ruff, Sara Kirvell, Gemma Johnson, Harvinder S. Dhillon, Stephen A. Bustin |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-06-01
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Series: | Biomolecular Detection and Quantification |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214753515000273 |
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