Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn

Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn

Epithelial cells are involved in the regulation of innate and adaptive immunity in response to different stresses. The purpose of this study was to investigate if alkali-injured corneal epithelia activate innate immunity through the nucleotide-binding oligomerization domain-containing protein (NOD)-...

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Bibliographic Details
Main Authors: Fang Bian, Yangyan Xiao, Mahira Zaheer, Eugene A. Volpe, Stephen C. Pflugfelder, De-Quan Li, Cintia S. de Paiva
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:International Journal of Molecular Sciences
Subjects:
alkali injury
NLRP3 inflammasome
sodium butyrate
β-hydroxybutyric acid
Online Access:http://www.mdpi.com/1422-0067/18/3/562

Internet

http://www.mdpi.com/1422-0067/18/3/562

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