Targeted overexpression of amelotin disrupts the microstructure of dental enamel.

We have previously identified amelotin (AMTN) as a novel protein expressed predominantly during the late stages of dental enamel formation, but its role during amelogenesis remains to be determined. In this study we generated transgenic mice that produce AMTN under the amelogenin (Amel) gene promote...

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Bibliographic Details
Main Authors: Rodrigo S Lacruz, Yohei Nakayama, James Holcroft, Van Nguyen, Eszter Somogyi-Ganss, Malcolm L Snead, Shane N White, Michael L Paine, Bernhard Ganss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335167?pdf=render