A Systematic Literature Review and Meta-Regression Analysis on Early-Life Energy Restriction and Cancer Risk in Humans.

BACKGROUND:In animal models, long-term moderate energy restriction (ER) is reported to decelerate carcinogenesis, whereas the effect of severe ER is inconsistent. The impact of early-life ER on cancer risk has never been reviewed systematically and quantitatively based on observational studies in hu...

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Bibliographic Details
Main Authors: Rachel J J Elands, Colinda C J M Simons, Martien van Dongen, Leo J Schouten, Bas A J Verhage, Piet A van den Brandt, Matty P Weijenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5028056?pdf=render