Wallerian-like axonal degeneration in the optic nerve after excitotoxic retinal insult: an ultrastructural study

<p>Abstract</p> <p>Background</p> <p>Excitotoxicity is involved in the pathogenesis of a number neurodegenerative diseases, and axonopathy is an early feature in several of these disorders. In models of excitotoxicity-associated neurological disease, an excitotoxin deli...

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Bibliographic Details
Main Authors: Saggu Sarabjit K, Chotaliya Hiren P, Blumbergs Peter C, Casson Robert J
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/11/97