Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation

Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation

Cystathionine γ lyase (CSE) is the major source of hydrogen sulfide-derived species (H2Sn) in endothelial cells and plays an important role in protecting against atherosclerosis. Here we investigated the molecular mechanisms underlying the regulation of CSE expression in endothelial cells by fluid s...

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Bibliographic Details
Main Authors: Sofia-Iris Bibli, Jiong Hu, Matthias S. Leisegang, Janina Wittig, Sven Zukunft, Andrea Kapasakalidi, Beate Fisslthaler, Diamantis Tsilimigras, Georgios Zografos, Konstantinos Filis, Ralf P. Brandes, Andreas Papapetropoulos, Fragiska Sigala, Ingrid Fleming
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719312261

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http://www.sciencedirect.com/science/article/pii/S2213231719312261

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