Patterns, Profiles, and Parsimony: Dissecting Transcriptional Signatures From Minimal Single-Cell RNA-Seq Output With SALSA

Patterns, Profiles, and Parsimony: Dissecting Transcriptional Signatures From Minimal Single-Cell RNA-Seq Output With SALSA

Single-cell RNA sequencing (scRNA-seq) technologies have precipitated the development of bioinformatic tools to reconstruct cell lineage specification and differentiation processes with single-cell precision. However, current start-up costs and recommended data volumes for statistical analysis remai...

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Bibliographic Details
Main Authors: Oswaldo A. Lozoya, Kathryn S. McClelland, Brian N. Papas, Jian-Liang Li, Humphrey H.-C. Yao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
scRNA-seq
NGS
RNA
single cells
heterogeneity
sparsity
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.511286/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.511286/full

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