A human phospholipid phosphatase activated by a transmembrane control module

A human phospholipid phosphatase activated by a transmembrane control module

In voltage-sensitive phosphatases (VSPs), a transmembrane voltage sensor domain (VSD) controls an intracellular phosphoinositide phosphatase domain, thereby enabling immediate initiation of intracellular signals by membrane depolarization. The existence of such a mechanism in mammals has remained el...

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Bibliographic Details
Main Authors: Christian R. Halaszovich, Michael G. Leitner, Angeliki Mavrantoni, Audrey Le, Ludivine Frezza, Anja Feuer, Daniela N. Schreiber, Carlos A. Villalba-Galea, Dominik Oliver
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Journal of Lipid Research
Subjects:
phosphoinositides
voltage sensor
electrochemical coupling
ion channel
lipid signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520412441

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http://www.sciencedirect.com/science/article/pii/S0022227520412441

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