Axon regeneration after optic nerve injury in rats can be improved via PirB knockdown in the retina

Axon regeneration after optic nerve injury in rats can be improved via PirB knockdown in the retina

Abstract Background In the central nervous system (CNS), three types of myelin-associated inhibitors (MAIs) exert major inhibitory effects on nerve regeneration: Nogo-A, myelin-associated glycoprotein (MAG), and oligodendrocyte-myelin glycoprotein (OMgp). MAIs have two co-receptors, Nogo receptor (N...

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Bibliographic Details
Main Authors: Mei Yang, Lan Jian, Wei Fan, Xing Chen, Huan Zou, Yanming Huang, Xiaofan Chen, Yuan-Guo Zhou, Rongdi Yuan
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cell & Bioscience
Subjects:
Regeneration
Müller cell
Optic
Retina ganglion cell injury
AAV
Online Access:https://doi.org/10.1186/s13578-021-00670-w

Internet

https://doi.org/10.1186/s13578-021-00670-w

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