MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology.
Age-related increases in monoamine oxidase B (MAO-B) may contribute to neurodegeneration associated with Parkinson's disease (PD). The MAO-B inhibitor deprenyl, a long-standing antiparkinsonian therapy, is currently used clinically in concert with the dopamine precursor L-DOPA. Clinical studies...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-02-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2229649?pdf=render |