Incorporating distant sequence features and radial basis function networks to identify ubiquitin conjugation sites.

Ubiquitin (Ub) is a small protein that consists of 76 amino acids about 8.5 kDa. In ubiquitin conjugation, the ubiquitin is majorly conjugated on the lysine residue of protein by Ub-ligating (E3) enzymes. Three major enzymes participate in ubiquitin conjugation. They are E1, E2 and E3 which are resp...

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Bibliographic Details
Main Authors: Tzong-Yi Lee, Shu-An Chen, Hsin-Yi Hung, Yu-Yen Ou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3052307?pdf=render