Use of Post-transplant Cyclophosphamide Treatment to Build a Tolerance Platform to Prevent Liquid and Solid Organ Allograft Rejection

Use of Post-transplant Cyclophosphamide Treatment to Build a Tolerance Platform to Prevent Liquid and Solid Organ Allograft Rejection

Corneal transplantation (CT) is the most frequent type of solid organ transplant (SOT) performed worldwide. Unfortunately, immunological rejection is the primary cause of graft failure for CT and therefore advances in immune regulation to induce tolerance remains an unmet medical need. Recently, our...

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Bibliographic Details
Main Authors: Casey O. Lightbourn, Dietlinde Wolf, Sabrina N. Copsel, Ying Wang, Brent J. Pfeiffer, Henry Barreras, Cameron S. Bader, Krishna V. Komanduri, Victor L. Perez, Robert B. Levy
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
cyclophosphamide
Treg
corneal transplantation
hematopoietic stem cell transplantation
tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.636789/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.636789/full

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