Synthesis of epoxide and vicinal diol regioisomers from docosahexaenoate methyl esters.

Docosahexaenoic acid (22:6(n-3)) was recently shown to be metabolized by liver microsomes to vicinal diol regioisomers. To identify the diols, and to compare their biological actions with those of epoxide precursors, we developed a chemical method to synthesize microgram to milligram amounts of epox...

Full description

Bibliographic Details
Main Authors: M VanRollins, P D Frade, O A Carretero
Format: Article
Language:English
Published: Elsevier 1989-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520383759