Synthesis of epoxide and vicinal diol regioisomers from docosahexaenoate methyl esters.
Docosahexaenoic acid (22:6(n-3)) was recently shown to be metabolized by liver microsomes to vicinal diol regioisomers. To identify the diols, and to compare their biological actions with those of epoxide precursors, we developed a chemical method to synthesize microgram to milligram amounts of epox...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
1989-02-01
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Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520383759 |