Allergens induce enhanced bronchoconstriction and leukotriene production in C5 deficient mice
<p>Abstract</p> <p>Background</p> <p>Previous genetic analysis has shown that a deletion in the complement component 5 gene-coding region renders mice more susceptible to allergen-induced airway hyperresponsiveness (AHR) due to reduced IL-12 production. We investigated...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-10-01
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| Series: | Respiratory Research |
| Online Access: | http://respiratory-research.com/content/7/1/129 |