Simulations for designing and interpreting intervention trials in infectious diseases

Simulations for designing and interpreting intervention trials in infectious diseases

Abstract Background Interventions in infectious diseases can have both direct effects on individuals who receive the intervention as well as indirect effects in the population. In addition, intervention combinations can have complex interactions at the population level, which are often difficult to...

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Bibliographic Details
Main Authors: M. Elizabeth Halloran, Kari Auranen, Sarah Baird, Nicole E. Basta, Steven E. Bellan, Ron Brookmeyer, Ben S. Cooper, Victor DeGruttola, James P. Hughes, Justin Lessler, Eric T. Lofgren, Ira M. Longini, Jukka-Pekka Onnela, Berk Özler, George R. Seage, Thomas A. Smith, Alessandro Vespignani, Emilia Vynnycky, Marc Lipsitch
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Medicine
Subjects:
Clinical trial design
Infectious diseases
Mathematical modeling
Simulations
Vaccine
Online Access:http://link.springer.com/article/10.1186/s12916-017-0985-3

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http://link.springer.com/article/10.1186/s12916-017-0985-3

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