Cyclophilin a signaling induces pericyte-associated blood-brain barrier disruption after subarachnoid hemorrhage

Cyclophilin a signaling induces pericyte-associated blood-brain barrier disruption after subarachnoid hemorrhage

Abstract Objective The potential roles and mechanisms of pericytes in maintaining blood–brain barrier (BBB) integrity, which would be helpful for the development of therapeutic strategies for subarachnoid hemorrhage (SAH), remain unclear. We sought to provide evidence on the potential role of pericy...

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Bibliographic Details
Main Authors: Pengyu Pan, Hengli Zhao, Xuan Zhang, Qiang Li, Jie Qu, Shilun Zuo, Fan Yang, Guobiao Liang, John H. Zhang, Xin Liu, Haiyang He, Hua Feng, Yujie Chen
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Neuroinflammation
Subjects:
Subarachnoid Hemorrhage
Pericyte
Blood–brain barrier
Cyclophilin A
CD147
Online Access:https://doi.org/10.1186/s12974-020-1699-6

Internet

https://doi.org/10.1186/s12974-020-1699-6

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