Maternal Transmission of Human OGG1 Protects Mice Against Genetically- and Diet-Induced Obesity Through Increased Tissue Mitochondrial Content

Obesity and related metabolic disorders are pressing public health concerns, raising the risk for a multitude of chronic diseases. Obesity is multi-factorial disease, with both diet and lifestyle, as well as genetic and developmental factors leading to alterations in energy balance. In this regard,...

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Bibliographic Details
Main Authors: Natalie Burchat, Priyanka Sharma, Hong Ye, Sai Santosh Babu Komakula, Agnieszka Dobrzyn, Vladimir Vartanian, R. Stephen Lloyd, Harini Sampath
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.718962/full