Initiating buprenorphine to treat opioid use disorder without prerequisite withdrawal: a systematic review

Abstract Background Opioid withdrawal symptoms prior to buprenorphine initiation may be intolerable and as a result, alternative strategies have emerged. We aim to systematically review the efficacy and safety of buprenorphine initiation that aims to omit prerequisite withdrawal. Methods We conducte...

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Bibliographic Details
Main Authors: K. K. Adams, M. Machnicz, D. M. Sobieraj
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Addiction Science & Clinical Practice
Subjects:
Online Access:https://doi.org/10.1186/s13722-021-00244-8