The diagnosis of tuberculous meningitis in adults and adolescents: protocol for a systematic review and individual patient data meta-analysis to inform a multivariable prediction model [version 3; peer review: 2 approved]

Background: Tuberculous meningitis (TBM) is the most lethal and disabling form of tuberculosis. Delayed diagnosis and treatment, which is a risk factor for poor outcome, is caused in part by lack of availability of diagnostic tests that are both rapid and accurate. Several attempts have been made to...

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Bibliographic Details
Main Authors: Tom Boyles, Anna Stadelman, Jayne P. Ellis, Fiona V. Cresswell, Vittoria Lutje, Sean Wasserman, Nicki Tiffin, Robert Wilkinson
Format: Article
Language:English
Published: Wellcome 2021-01-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-19/v3