Nicotinamide inhibits melanoma in vitro and in vivo

Nicotinamide inhibits melanoma in vitro and in vivo

Abstract Background Even though new therapies are available against melanoma, novel approaches are needed to overcome resistance and high-toxicity issues. In the present study the anti-melanoma activity of Nicotinamide (NAM), the amide form of Niacin, was assessed in vitro and in vivo. Methods Human...

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Bibliographic Details
Main Authors: Francesca Scatozza, Federica Moschella, Daniela D’Arcangelo, Stefania Rossi, Claudio Tabolacci, Claudia Giampietri, Enrico Proietti, Francesco Facchiano, Antonio Facchiano
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Melanoma
Nicotinamide
Vitamin B3
Melanoma mouse-animal model
Metabolism
Sirtuin 2
Online Access:http://link.springer.com/article/10.1186/s13046-020-01719-3

Internet

http://link.springer.com/article/10.1186/s13046-020-01719-3

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