Compositional and Material Properties of Rat Bone after Bisphosphonate and/or Strontium Ranelate Drug Treatment

Purpose. We investigated elemental strontium and/or bisphosphonate drug incorporation upon the compositional and biomechanical properties of vertebral bone, in a rat model of Osteoporosis secondary to ovariectomy. Methods. Six month old female rats were ovariectomized (OVX) and divided into untreate...

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Bibliographic Details
Main Authors: Yuchin Wu, Samer M Adeeb, M. John Duke, David Munoz-Paniagua, Michael R. Doschak
Format: Article
Language:English
Published: Canadian Society for Pharmaceutical Sciences 2013-01-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/16992