A micellar on-pathway intermediate step explains the kinetics of prion amyloid formation.

In a previous work by Alvarez-Martinez et al. (2011), the authors pointed out some fallacies in the mainstream interpretation of the prion amyloid formation. It appeared necessary to propose an original hypothesis able to reconcile the in vitro data with the predictions of a mathematical model descr...

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Bibliographic Details
Main Authors: Erwan Hingant, Pascaline Fontes, Maria Teresa Alvarez-Martinez, Jacques-Damien Arnaud, Jean-Pierre Liautard, Laurent Pujo-Menjouet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4125056?pdf=render