Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation[S]

The hypothesis tested in this study was that cholesterol esterification by ACAT2 would increase cholesterol absorption efficiency by providing cholesteryl ester (CE) for incorporation into chylomicrons. The assumption was that absorption would be proportional to Acat2 gene dosage. Male ACAT2+/+, ACA...

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Bibliographic Details
Main Authors: Tam M. Nguyen, Janet K. Sawyer, Kathryn L. Kelley, Matthew A. Davis, Lawrence L. Rudel
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752040803X