Retrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activation.
In evolution strategies aimed at isolating molecules with new functions, screening for the desired phenotype is generally performed in vitro or in bacteria. When the final goal of the strategy is the modification of the human cell, the mutants selected with these preliminary screenings may fail to c...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-08-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3426553?pdf=render |