Evaluation of a real-time PCR assay for detection and quantification of bacterial DNA directly in blood of preterm neonates with suspected late-onset sepsis

Evaluation of a real-time PCR assay for detection and quantification of bacterial DNA directly in blood of preterm neonates with suspected late-onset sepsis

Abstract Background Rapid and accurate diagnosis of neonatal sepsis is highly warranted because of high associated morbidity and mortality. The aim of this study was to evaluate the performance of a novel multiplex PCR assay for diagnosis of late-onset sepsis and to investigate the value of bacteria...

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Bibliographic Details
Main Authors: Marre van den Brand, Frank A. M. van den Dungen, Martine P. Bos, Mirjam M. van Weissenbruch, A. Marceline van Furth, Annemieke de Lange, Anna Rubenjan, Remco P. H. Peters, Paul H. M. Savelkoul
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Critical Care
Subjects:
Molecular diagnosis
Late-onset sepsis
Neonatology
Real-time PCR
Bacterial DNA load
Bacteremia
Online Access:http://link.springer.com/article/10.1186/s13054-018-2010-4

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http://link.springer.com/article/10.1186/s13054-018-2010-4

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