Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)

Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)

Abstract Background Genetic testing for BRCA1/2 genes is widely used as a strategy to reduce incidence and morbidity of hereditary breast and ovarian cancer (HBOC). The purpose of this study is to analyse the demographic and molecular characteristics of BRCA germline mutations in Navarra, Spain, and...

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Main Authors: Ainara Ruiz de Sabando, Edurne Urrutia Lafuente, Fermín García-Amigot, Angel Alonso Sánchez, Lourdes Morales Garofalo, Sira Moreno, Eva Ardanaz, Maria A. Ramos-Arroyo
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Cancer
Subjects:
Hereditary breast and ovarian cancer (HBOC)
BRCA1/2
Recurrent mutations
Demographics
Sporadic breast and ovarian cancer
Laterality and stage of tumors
Online Access:http://link.springer.com/article/10.1186/s12885-019-6277-x

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http://link.springer.com/article/10.1186/s12885-019-6277-x

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