New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes

New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes

Cytoplasmic FMRP interacting protein 1 (CYFIP1) is a candidate gene for intellectual disability (ID), autism, schizophrenia and epilepsy. It is a member of a family of proteins that is highly conserved during evolution, sharing high homology with its Drosophila homolog, dCYFIP. CYFIP1 interacts with...

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Bibliographic Details
Main Authors: Sabiha Abekhoukh, H. Bahar Sahin, Mauro Grossi, Samantha Zongaro, Thomas Maurin, Irene Madrigal, Daniele Kazue-Sugioka, Annick Raas-Rothschild, Mohamed Doulazmi, Pilar Carrera, Andrea Stachon, Steven Scherer, Maria Rita Drula Do Nascimento, Alain Trembleau, Ignacio Arroyo, Peter Szatmari, Isabel M. Smith, Montserrat Milà, Adam C. Smith, Angela Giangrande, Isabelle Caillé, Barbara Bardoni
Format: Article
Language:English
Published: The Company of Biologists 2017-04-01
Series:Disease Models & Mechanisms
Subjects:
Fragile X
Intellectual disability
Autism
CYFIP1
BP1-BP2 deletion
Online Access:http://dmm.biologists.org/content/10/4/463

Internet

http://dmm.biologists.org/content/10/4/463

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