LDL-induced impairment of human vascular smooth muscle cells repair function is reversed by HMG-CoA reductase inhibition.

LDL-induced impairment of human vascular smooth muscle cells repair function is reversed by HMG-CoA reductase inhibition.

Growing human atherosclerotic plaques show a progressive loss of vascular smooth muscle cells (VSMC) becoming soft and vulnerable. Lipid loaded-VSMC show impaired vascular repair function and motility due to changes in cytoskeleton proteins involved in cell-migration. Clinical benefits of statins re...

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Bibliographic Details
Main Authors: Teresa Padró, Roberta Lugano, Maisa García-Arguinzonis, Lina Badimon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3373563?pdf=render

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http://europepmc.org/articles/PMC3373563?pdf=render

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