Using the R Package crlmm for Genotyping and Copy Number Estimation

Using the R Package crlmm for Genotyping and Copy Number Estimation

Genotyping platforms such as Affymetrix can be used to assess genotype-phenotype as well as copy number-phenotype associations at millions of markers. While genotyping algorithms are largely concordant when assessed on HapMap samples, tools to assess copy number changes are more variable and often d...

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Bibliographic Details
Main Authors: Robert B. Scharpf, Rafael A. Irizarry, Matthew E. Ritchie, Benilton Carvalho, Ingo Ruczinski
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2011-05-01
Series:Journal of Statistical Software
Subjects:
copy number
batch effects
robust
multilevel model
high-throughput
oligonucleotide array
Online Access:http://www.jstatsoft.org/v40/i12/paper

Internet

http://www.jstatsoft.org/v40/i12/paper

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