GDF15 promotes glioma stem cell-like phenotype via regulation of ERK1/2–c-Fos–LIF signaling

GDF15 promotes glioma stem cell-like phenotype via regulation of ERK1/2–c-Fos–LIF signaling

Abstract Growth differentiation factor 15 (GDF15), a member of the transforming growth factor β family, is associated with tumor progression, metastasis, and cell apoptosis. However, controversy persists regarding the role of GDF15 in different tumor types, and its function in glioma stem cells (GSC...

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Bibliographic Details
Main Authors: Shan Zhu, Ning Yang, Yi Guan, Xue Wang, Guoxia Zang, Xinping Lv, Shuanglin Deng, Wan Wang, Tete Li, Jingtao Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-020-00395-8

Internet

https://doi.org/10.1038/s41420-020-00395-8

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