Nucleus Accumbens Shell Orexin-1 Receptors Are Critical Mediators of Binge Intake in Excessive-Drinking Individuals

Nucleus Accumbens Shell Orexin-1 Receptors Are Critical Mediators of Binge Intake in Excessive-Drinking Individuals

Excessive, binge alcohol drinking is a potent and pernicious obstacle to treating alcohol use disorder (AUD), and heavy-drinking humans are responsible for much of the substantial costs and harms of AUD. Thus, identifying key mechanisms that drive intake in higher-drinking individuals may provide im...

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Bibliographic Details
Main Authors: Kelly Lei, Claudina Kwok, David Darevsky, Scott A. Wegner, JiHwan Yu, Lisa Nakayama, Vincent Pedrozo, Lexy Anderson, Shahbaj Ghotra, Mary Fouad, Frederic W. Hopf
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroscience
Subjects:
alcohol
nucleus accumbens
shell
orexin
SB-334867
excessive drinkers
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00088/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00088/full

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