Kathon Induces Fibrotic Inflammation in Lungs: The First Animal Study Revealing a Causal Relationship between Humidifier Disinfectant Exposure and Eosinophil and Th2-Mediated Fibrosis Induction

Currently available toxicity data on humidifier disinfectants are primarily limited to polyhexamethylene guanidine phosphate-induced lung fibrosis. We, therefore, investigated whether the sterilizer component Kathon, which is a mixture of chloromethylisothiazolinone and methylisothiazolinone, induce...

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Bibliographic Details
Main Authors: Mi-Kyung Song, Dong Im Kim, Kyuhong Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
Th2
Online Access:https://www.mdpi.com/1420-3049/25/20/4684