Leucine Supplementation Decreases <i>HDAC4</i> Expression and Nuclear Localization in Skeletal Muscle Fiber of Rats Submitted to Hindlimb Immobilization

In this study we surveyed a rat skeletal muscle RNA-Seq for genes that are induced by hindlimb immobilization and, in turn, become attenuated by leucine supplementation. This approach, in search of leucine-atrophy protection mediating genes, identified histone deacetylase 4 (<i>HDAC4</i>...

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Bibliographic Details
Main Authors: Paula K. N. Alves, André Cruz, William J. Silva, Siegfried Labeit, Anselmo S. Moriscot
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/12/2582