Alterations in Expression and Function of ABC Family Transporters at Blood-Brain Barrier under Liver Failure and Their Clinical Significances

Alterations in Expression and Function of ABC Family Transporters at Blood-Brain Barrier under Liver Failure and Their Clinical Significances

Liver failure is often associated with hepatic encephalopathy, due to dyshomeostasis of the central nervous system (CNS). Under physiological conditions, the CNS homeostasis is precisely regulated by the blood-brain barrier (BBB). The BBB consists of brain microvessel endothelial cells connected wit...

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Bibliographic Details
Main Authors: Yilin Fan, Xiaodong Liu
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Pharmaceutics
Subjects:
blood-brain barrier
liver failure
P-glycoprotein
breast cancer resistance protein
multidrug resistance-associated proteins
hepatic encephalopathy
Online Access:http://www.mdpi.com/1999-4923/10/3/102

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http://www.mdpi.com/1999-4923/10/3/102

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