Accurate sequence variant genotyping in cattle using variation-aware genome graphs
Abstract Background Genotyping of sequence variants typically involves, as a first step, the alignment of sequencing reads to a linear reference genome. Because a linear reference genome represents only a small fraction of all the DNA sequence variation within a species, reference allele bias may oc...
| Main Authors: | , , |
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| Format: | Article |
| Language: | deu |
| Published: |
BMC
2019-05-01
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| Series: | Genetics Selection Evolution |
| Online Access: | http://link.springer.com/article/10.1186/s12711-019-0462-x |