The ABCA1 blocking agent probucol decreases capacitation in ejaculated dog spermatozoa

Abstract Background The ATP binding cassette (ABC) transporters participate in the cholesterol and phospholipid transport within and through cell membranes of many cells including spermatozoa. Cholesterol efflux is important for capacitation of spermatozoa. ABCA1 expression has been assessed in cani...

Full description

Bibliographic Details
Main Authors: Sabine Schäfer-Somi, Sven Budik
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Acta Veterinaria Scandinavica
Subjects:
Online Access:https://doi.org/10.1186/s13028-019-0500-2