Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock

Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock

Abstract Background Platelets have been demonstrated to be potent activators of neutrophil extracellular trap (NET) formation during sepsis. However, the mediators and molecular pathways involved in human platelet-mediated NET generation remain poorly defined. Circulating plasma exosomes mostly orig...

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Bibliographic Details
Main Authors: Yang Jiao, Weiwei Li, Wei Wang, Xingyu Tong, Ran Xia, Jie Fan, Jianer Du, Chengmi Zhang, Xueyin Shi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Critical Care
Subjects:
Septic shock
Neutrophil extracellular traps
Platelets
Exosomes
HMGB1
miRNAs
Online Access:http://link.springer.com/article/10.1186/s13054-020-03082-3

Internet

http://link.springer.com/article/10.1186/s13054-020-03082-3

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