Exposure of chlorpromazine to 266 nm laser beam generates new species with antibacterial properties: contributions to development of a new process for drug discovery.

<h4>Introduction</h4>Phenothiazines when exposed to white light or to UV radiation undergo a variety of reactions that result in degradation of parental compound and formation of new species. This process is slow and may be sped up with exposure to high energy light such as that produced...

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Main Authors: Mihail Lucian Pascu, Balazs Danko, Ana Martins, Nikoletta Jedlinszki, Tatiana Alexandru, Viorel Nastasa, Mihai Boni, Andra Militaru, Ionut Relu Andrei, Angela Staicu, Attila Hunyadi, Seamus Fanning, Leonard Amaral
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23405212/?tool=EBI