Study of aversive and p38 mapk-inhibitory properties of kappa-agonist with analgesic activity – compound RU-1205

Introduction: The clinical use of kappa-opioid agonists, despite their lack of significant drug potential, is limited by the development of severe sedation, dysphoria, depression, and anhedonia. To this date, there are kappa-opioid receptor agonists lacking these side effec...

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Bibliographic Details
Main Authors: Alexander A. Spasov, Edwin E. Zvartau, Olesya Iu. Grechko, Natalya V. Eliseeva, Yuliya V. Semenova, Olga A. Dravolina, Pavel M Vasiliev, Vera A. Anisimova
Format: Article
Language:English
Published: Pensoft Publishers 2020-09-01
Series:Research Results in Pharmacology
Online Access:https://rrpharmacology.pensoft.net/article/54558/download/pdf/